Estradiol-induced alteration of very-low-density lipoprotein assembly. Possible competition among apoproteins for incorporation into nascent very-low-density lipoprotein.
نویسندگان
چکیده
منابع مشابه
Very-low density lipoprotein metabolism.
This manuscript was presented in part at the 31st Annual Meeting of the Council on Arteriosclerosis, American Society for the Study of Arteriosclerosis, American Heart Association. 1977. Circulation. 56(Suppl. III): 22. (Abstr.) Received for publication 2 December 1977 and in revised form 9 February 1978. and apoC) contained by negative staining, many disklike structures. The study demonstrated...
متن کاملVery Low Density Lipoprotein (VLDL)
Triglyceride (TG) or more accurately triacylglycerol is simply a compound of three acyl groups (fatty acids) attached to a glycerol molecule. They are easily measured in the laboratory and reported as serum TG level: it actually refers to all of the TG that are being trafficked within all of the lipoproteins that exist in a deciliter of plasma. A physiologic fasting TG concentration is on avera...
متن کاملConversion of human low density lipoprotein into a very low density lipoprotein-like particle in vitro.
The lipid substrate specificity of Manduca sexta lipid transfer particle (LTP) was examined in in vitro lipid transfer assays employing high density lipophorin and human low density lipoprotein (LDL) as donor/acceptor substrates. Unesterified cholesterol was found to exchange spontaneously between these substrate lipoproteins, and the extent of transfer/exchange was not affected by LTP. By cont...
متن کاملAssembly and secretion of hepatic very-low-density lipoprotein.
In contrast to water-soluble fuels such as glucose or ketone bodies, the use of lipids as an energy source for tissues has required the development of complex structures for their transport through the aqueous plasma. In the case of endogenously synthesized triacylglycerol this is achieved by the assembly and secretion of hepatic VLDL which provides the necessary stability in an aqueous medium....
متن کاملThe enzymology of hepatic very-low-density lipoprotein assembly.
The synthesis and export of triacylglycerol (TAG) by the liver provides mammals with an efficient means of transporting a powerful source of energy either for storage in adipose tissue or for utilization, predominantly by muscle tissue. On a molar basis, the transport of large quantities of energy as TAG may be achieved at relatively low concentrations of TAG in the blood plasma. Similar amount...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1984
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(17)42546-4